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Mabel Ruth Hokin was a biochemist who spent most of her professional career conducting fundamental research in the University of Wisconsin Medical School. She is most well known for the work she did early in her career, along with then-husband Lowell Hokin, in the study of stimulated phosphoinositide turnover in secretory tissues, a key component of transmembrane signaling and many other cell regulatory processes which became known as the 'PI Effect'.〔 〕 == Early life == Mabel Ruth Neaverson was born to working-class parents in the Heeley district of Sheffield, England in early 1924. She had two younger sisters, Mary and Dorothy. Mabel took to academic pursuits at an early age, excelling in elementary and grammar school as well as at bible scholarship. She spent 1942 to 1943 working in the Women's Land Army, where, among other things, she helped administer a refugee camp for Czech Jews. (Mabel converted to Judaism ten years later.) She also became interested in costume design and theater, where she met her first husband, actor and playwright (Dennis Davison ). Mabel worked as a technician in the Medical Research Council Unit for Research in Cell Metabolism under Hans Krebs at the University of Sheffield from 1943 to 1946, and enrolled as a student in 1946, continuing to work for Krebs. Krebs recognized Mabel's scientific mind and talent in the laboratory, and urged her to pursue doctoral work, which she began in 1949 after receiving her Bachelor of Science Honors degree in Physiology. She did her graduate research under Quentin Gibson in the Physiology department. In a short time, Mabel met Krebs' graduate student Lowell Hokin, and the two began a romantic as well as professional relationship. Mabel (received her Ph.D. ) in 1952. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Mabel Hokin」の詳細全文を読む スポンサード リンク
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